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Cities in South Carolina by population Charleston — 152,014Columbia — 138,019Greenville — 71,755Goose Creek — 46,964Florence — 40,205Greer — 39,191Hilton Head Island — 37,805Aiken — 32,334Bluffton — 31,323Anderson — 29,563Fort Mill — 28,281Carolina Forest — 26,373Conway — 26,082Lexington — 24,132Easley — 23,942Greenwood — 22,527Hanahan — 21,119Five Forks — 19,093Clemson — 17,759Berea — 16,642Ladson — 16,261Dentsville — 15,396Lake Wylie — 15,177Gantt — 15,057Cayce — 13,718Beaufort — 13,660Gaffney — 12,612Boiling Springs — 12,609Irmo — 11,799James Island — 11,738Fountain Inn — 11,307Garden City — 10,820Forest Acres — 10,491Laurens — 9,307Hardeeville — 9,293Lancaster — 8,738Georgetown — 8,511Camden — 8,025Clinton — 7,624Forestbrook — 7,450Hartsville — 7,422Burton — 7,132Lake Murray of Richland — 7,057Clover — 7,013Homeland Park — 6,944Centerville — 6,860Bennettsville — 6,798Clemson University — 6,434Dillon — 6,406Darlington — 6,128Lake City — 6,032Laurel Bay — 5,627Belvedere — 5,458Hollywood — 5,330Blythewood — 5,309Central — 5,299Chester — 5,241Cheraw — 5,024Browse all states →